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38 Years
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Medical-Grade Skincare for Dry, Cracked, and Irritated Skin
Formula 2 Skin Care was founded in 1988 by pharmacist Mark Isabella, who developed a proprietary skin care cream formula to address severe dryness and irritation. Our pharmacist-formulated products, created in collaboration with Mark's father Sam, have been trusted by medical professionals for decades. We specialize in solutions for conditions like eczema, psoriasis, incontinence care, and wound healing, with formulations free of fragrance, alcohol, and lanolin. Our products are recommended by doctors and nurses in hospitals and clinics nationwide, reflecting our commitment to clinical efficacy.

Manufactured in a state-of-the-art facility near Daytona Beach, Florida, we expanded nationally in 2013 to make our medical-grade skincare accessible to all. Customer testimonials highlight transformative results for conditions ranging from radiation burns to diabetic skin complications. We maintain rigorous quality standards while offering direct-to-consumer sales with free continental U.S. shipping. Our mission remains focused on becoming a household name through reliable, science-backed skincare solutions that deliver measurable relief.
Services
Skin Care Cream Rectal Care Cream Barrier Spray Wound Care Products Eczema Treatment
Details
  • Year established: 1988
Highlights and features
  • Pharmacist-developed formulas since 1988
  • Recommended by doctors and nurses nationwide
  • Manufactured in FDA-registered U.S. facilities
  • Free of fragrance, alcohol, and lanolin
  • Free continental U.S. shipping on all orders
What people say
Healed bed sores Rapid pain relief Smoothed cracked skin Recommended by nurses Effective for radiation burns
Services
Skin Care Cream
Our pharmacist-formulated skin care cream addresses severe dryness and cracking through a triple-action formula. Designed for conditions like eczema and diabetic skin complications, it restores elasticity while creating a protective barrier. Clinical testing confirms its effectiveness for both preventive care and active healing of compromised skin surfaces.
Rectal Care Cream
This targeted cream provides rapid relief for anorectal discomfort and irritation. Its medicated formula reduces inflammation and promotes tissue healing while maintaining a gentle barrier against further irritation. Developed with input from medical professionals, it's specifically formulated for sensitive post-procedural and chronic condition management.
Barrier Spray
Our alcohol-free barrier spray creates a breathable protective layer for incontinence care and diaper rash prevention. The fast-absorbing formula maintains skin pH balance while forming a moisture-resistant shield. Clinically proven to prevent irritation in both pediatric and geriatric care applications.
Wound Care Products
Medical-grade formulations accelerate healing for minor wounds and skin abrasions. The non-stinging formula supports natural tissue repair while protecting against bacterial contamination. Recommended by wound care centers for both acute injuries and chronic non-healing wounds in clinical settings.
Eczema Treatment
Dermatologist-recommended treatment for eczema and psoriasis flare-ups. The corticosteroid-free formula reduces redness and itching through moisturizing agents and skin barrier restoration. Safe for long-term use on sensitive areas, with documented success in reducing flare-up frequency and severity.
People
Mark Isabella
Founder
Pharmacist and co-developer of Formula 2's proprietary skincare line. With over 35 years in pharmaceutical formulation, he created the original cream in 1988 that became a medical community staple. Expanded the product nationally in 2013 after decades of hospital and clinic usage.
Sam Isabella
Co-Founder
Experienced pharmacist who mentored his son Mark in skincare formulation. Contributed decades of pharmaceutical expertise to refine the original formula. His clinical background shaped the product's focus on medical-grade effectiveness while maintaining over-the-counter accessibility.
Questions
What skin conditions does Formula 2 treat?
Formula 2 addresses dry cracked skin, eczema, psoriasis, incontinence care, wound healing, radiation burns, and hemorrhoid irritation through specialized formulations.
Are Formula 2 products FDA approved?
Our products are manufactured in FDA-registered facilities following strict quality standards, though over-the-counter skincare products don't require individual FDA approval.
Can I use Formula 2 products on sensitive skin?
Yes - our formulas are free of fragrance, alcohol, lanolin, and zinc oxide, making them suitable for the most sensitive skin types.
Is Formula 2 available in stores?
Find Formula 2 in participating independent pharmacies nationwide, through hospital supply chains, and directly via our website with free U.S. shipping.
Does Formula 2 offer a money-back guarantee?
Yes, we stand by our product's effectiveness with a complete satisfaction guarantee for all unopened merchandise.
How should I apply Formula 2 products?
Apply liberally to affected areas as needed, following specific medical instructions for clinical applications. No prescription required for over-the-counter use.
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Reviews (1)
April Iverson
Sep 18, 2020 Report
This Formula 2 Skin Care Cream, has helped me so much. I have Mild Congestive Heartfailure and I retain fluid occasionally, causing my skin to be very unhappy and leaving rough patches at the base of my toes. I tried everything, different costly creams and now I'm on my 3rs tube of Formula 2! Thank you so much